First Time Progesterone User's Guide
When using natural progesterone cream for the first time (or even changing brands, for that matter), it is important to understand that the body needs time to adjust. Symptoms may change or increase for a time, but if they do, it’s usually just for a few days. If the symptoms last longer than that, it is usually indicative of not being used correctly – as in too little, or not often enough. In most cases, a minimum 2-6 months is required for total adjustment of the body and for progesterone to become dominant over estrogen as the desired result.